in vitro MEA

Cost-Effective MEA Platform for Simultaneous Stimulation and Recording — Incubator-ready.

Adaptive. Reliable.

Moisture-resistant, Perfect Signal

Moisture-resistant design
for incubator compatibility

Engineered for reliable operation within humid, temperature-controlled incubating chambers.

Fully shielded
and grounded enclosure

Minimizes electrical noise and interference to deliver the highest possible signal quality.

Customizable, Wide Compaible

Ensures accurate, repeatable alignment and seamless compatibility with MEAs from leading commercial vendors.

Optical Access

Integrated backside window allows concurrent microscopic inspection and imaging during experiments.

Tool-free

Once the headstage is installed, routine access to the MEA electrode is fast and tool-free using the captive screws.

MEA Platform Features

MEA Headstage
Configuration

Product
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SKU
HSSR64-60MEA
Lead time
3 Weeks
MEA Headstage
No items found.

Switchable Stimulate & Recording

Run XDAQ in XR/XSR Mode

Moisture Resistant,
Incubator-ready

The MEA interface supports high-channel, high-fidelity signal acquisition with integrated stimulation, built in a moisture-resistant, fully shielded and grounded enclosure to help preserve signal quality in humid, temperature-controlled environments.

Powerful Built-in,
Synchronized Video Capture

  • Backside MEA Optical Access
  • Standard cell-culture plate footprint

Completely Tool-free

1. Unscrew the six captive screws.

2. Separate the top and bottom housings.

3. Remove and replace the MEA cup.

4. Reattach and secure the housings.

Accessories

MEA Adapter

Browse
MEA Headstage
Customize
Browse

XDAQ Cable

Adapters

Browse
Browse

Cable

Custom
Gyro Headstage

Customize

Resources

Brochure
User Manual &
Other Resources

Specs

Headstage Specifications
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Recording Capability

Input Range

± 5mV

ADC Resolution

16-bit

Sampling Rate Per Channel

1k - 30k Hz

Input-referred Noise

2.4 µVrms

Min Detectable Signal

15 µV

Programmable Filters

100-20 kHz, DSP HPF
0.1-500 Hz LPF

in situ electrode impedance

Yes

CORE2

Base
Max
Recording Only (XR Mode)
512ch
Rec + Stimulation (XSR Mode)
16ch
32ch
Neuropixels 1 (NP Mode)
2-Port
# of Animal Monitored 2
Recording Only Experiment
8
Rec+Stimulation Experiment
1
2
Single Cable Probe
Recording Only Experiment
128ch
128ch
Rec+Stimulation Experiment 3
16ch
32ch
Synchronized GPIO4
Digital In (2.2-5.5V Logic High)
7ch
31ch
Digital Out (BNC 3.3, 5V configurable)
(DB25 3.3V)
7ch
31ch
ADC (16bit ±10V)
1ch
7ch
DAC (16bit ±10V)
1ch
7ch
Stim Compliance Voltage
± 7V
± 7V
Communication
Thunderbolt 3
PC Powering
15W
Latency (roundtrip)
< 1ms5
Software
Open-Ephys, XDAQ-RHX, Radiens
OS
Win, MacOS, Linux
Dimension (mm)
190x155x72
Weight (g)
900

ONE+

Base
Max
Recording Only (XR Mode)
512ch
1024ch
Rec + Stimulation (XSR Mode)
16ch
128ch
Neuropixels 1 (NP Mode)
4-Port
# of Animal Monitored 2
Recording Only Experiment
2
16
Rec+Stimulation Experiment
2
8
Single Cable Probe
Recording Only Experiment
256ch
Rec+Stimulation Experiment 3
32ch
64ch
Synchronized GPIO4
Digital In (2.2-5.5V Logic High)
8ch
32ch
Digital Out (BNC 3.3, 5V configurable)(DB25 3.3V)
8ch
32ch
ADC (16bit ±10V)
2ch
8ch
DAC (16bit ±10V)
2ch
8ch
Stim Compliance Voltage
+- 7V

+ 10 -4V

+ 4 -10V
+- 7V

+ 10 -4V

+ 4 -10V
Communication
Thunderbolt 3
PC Powering
60W
Latency (roundtrip)
< 1ms5
Software
Open-Ephys, XDAQ-RHX, Radiens
OS
Win, MacOS, Linux
Dimension (mm)
227x190x94
Weight (g)
3105

AIO

Base
Max
Recording Only (XR Mode)
1024ch
1024ch
Rec + Stimulation (XSR Mode)
128ch
128ch
Neuropixels 1 (NP Mode)
4-Port
4-Port
Guaranteed Video Capture
4ch
4ch
Optogenetics LED Driver
4ch
4ch
# of Animal Monitored 2
Recording Only Experiment
16
16
Rec+Stimulation Experiment
8
8
Single Cable Probe
Recording Only Experiment
256ch
256ch
Rec+Stimulation Experiment 3
32ch
64ch
Synchronized GPIO4
Digital In (2.2-5.5V Logic High)
8ch
32ch
Digital Out (BNC 3.3, 5V configurable)
(DB25 3.3V)
8ch
32ch
ADC (16bit ±10V)
2ch
8ch
DAC (16bit ±10V)
2ch
8ch
Stim Compliance
+- 7V

+ 10 -4V

+ 4 -10V
+- 7V

+ 10 -4V

+ 4 -10V
Communication
Thunderbolt 3
Communication
60W
Latency (roundtrip)8
< 1ms5
Software
Open-Ephys, XDAQ-RHX, Radiens
OS
Win, MacOS, Linux
Dimension (mm)
227x190x94
Weight (g)
3105

1.  Neuropixel support (NP Mode) can be configured without XR Mode or XSR Mode for passive probes.

2. Number of animals monitored can be increased using Port Expander, which provide each animal monitored with independent and isolated ground circuit.

3. Adpt-SR64 adapter is required to drive 64ch X3SR64 headstage.

4. IO Expander is required to increase the IO support.

5. Latency may vary with OS.

6. This product includes technology and knowhow developed by IMEC.

Stimulation Capability

Stimulation Driver

Constant Current

Deliverable Current per Channel

10nA - 2.55mA

Stimulation Compliance Voltage

14V

Stimulation Waveform

Biphasic, Triphasic, Burst waveform with 33us
minimal time steps